Presentation 

Each polyester polyurethane sponge contains 20mg flugestone acetate.

Uses    

In ewes and ewe-lambs, in combination with PMSG (Pregnant Mare Serum Gonadotrophin).

• Induction and synchronisation of oestrus and ovulation (non-cycling ewes during seasonal anoestrus ewe-lambs).
• Synchronisation of oestrus and ovulation (cycling ewes and ewe-lambs).
  

Dosage and administration

The dose is one sponge per animal irrespective of body weight, breed, type and season. 

The sponge is inserted intra-vaginally using an applicator.

It should remain in place for 14 days. At the end of this period, Chronogest CR is gently removed by pulling on its string.

To obtain an optimal synchronisation of ovulation, an injection of PMSG (range 300-700 i.u.) is administered (i.m.) at the time of sponge removal. 

In the case of fixed time AI, insemination at 55 hrs. after sponge removal is recommended.

Contra-indications, warnings, etc.

Do not use in pregnant females.

A muco-purulent discharge may occasionally be observed at sponge removal. It is not associated with clinical signs and does not alter fertility.

Repeated treatment with the product combined with PMSG may trigger the appearance of PMSG antibodies in some ewes. This in turn may affect the time of ovulation and result in reduced fertility when combined with fixed time artificial insemination at 55 hrs. following sponge removal.

The repeated use of sponges within one year has not been studied.

The use of a vaginal applicator designed for ewes or ewe-lambs is recommended to insert the sponges correctly and to avoid vaginal injuries.

The sponges should not be used in conjunction with alcohols, cresols, phenols, sheep dips or similar disinfectants.

Withdrawal periods:

For meat: 2 days after withdrawal of sponges.

For milk: zero days, including the treatment period.

Operator warnings:

Direct contact with the skin should be avoided. Personal protective clothing (single use gloves) should be worn when handling the product.  If accidental contact with the skin occurs, wash the affected zone with soap and water. Wash hands after treatment and before meals. Human exposure to this product can affect fertility.

Women who are pregnant, or suspected to be pregnant, should not use the product. 

FOR ANIMAL TREATMENT ONLY.   KEEP OUT OF THE REACH OF CHILDREN

Pharmaceutical precautions 

Do not store above 25°C.

Store the product in its original immediate packaging.

Once packaging is opened, any unused product should be discarded.

Any unused product or waste material should be disposed of in accordance with national requirements.

Legal Category

Package quantities 

Metallic polyester/low density polyethylene bags containing 25 sponges.

Further information

Nil.

Marketing Authorisation number 

Vm 06376/4042

Marketing Authorisation holder
Intervet International B.V.

The Netherlands

Represented   by:

IntervetUK Ltd.                

Walton Manor

Walton

Milton Keynes 

MK7 7AJ

Distributed in Northern Ireland by:

Intervet Ireland Ltd.

Magna Drive

Magna Business Park

Citywest Road

Dublin 24

Date of text preparation

July 2005.                                                                                

Item code: 037655                                                        74260/August2005/MP/2k