Presentation

Dimazon 5% Solution contains 50 mg/ml of Frusemide/Furosemide (as the monoethanolamine salt). It is a clear yellowish fluid. 

Uses

As a potent saluretic type of diuretic for parenteral administration to cattle, horses, cats and dogs. It is indicated in the treatment of oedemata associated with cardiac insufficiency, renal dysfunction, trauma and parasitic disease.   It is also recommended for the treatment of mammary oedema and limb oedemata.   The product gives rapid onset of diuretic action with increased sodium and water excretion and is effective even in cases where glomerular filtration is impaired.

Dosage and administration

In severe or refractory cases the dose may be doubled on a single occasion in the horse or cow. 

Dimazon 5% Solution may be administered by intramuscular injection in dogs and cats or intravenous injection for cattle, horses, dogs and cats, observing aseptic precautions.

Contra-indications, warnings, etc. 

The product is not indicated in cases of acute glomerular nephritis, renal failure with anuria, electrolyte deficiency disease or overdosage with digitalis. 

Do not use in horses intended for human consumption.

Do not use concurrently with aminoglycoside antibiotic treatment.

Too rapid injection in dogs may cause staggering and vomiting.

The therapeutic effect may be impaired by increased intake of drinking water. So far as the patient's condition allows, the amount of drinking water should be restricted during treatment. 

In pulmonary oedema of cardiac origin combined therapy with appropriate cardiac treatment is advisable.   Only during prolonged treatment is it necessary to monitor potassium balance.   Potassium supplements may be necessary.

Animals must not be slaughtered for human consumption during treatment.   Cattle may be slaughtered for human consumption only after 28 days from last treatment.

Milk withdrawal period: 

24 hours.

For animal treatment only.   Keep out of reach of children.

Pharmaceutical precautions 

Do not store above 25°C. Protect from light. 

Dimazon 5% Solution should not be mixed with other preparations. 

Following withdrawal of the first dose use the product within 28 days.   Discard unused material.

If the product is stored for a prolonged period below +18°C, crystalline precipitation may occur.   Do not use the product whilst the crystals are present.   The crystals may be re-dissolved by shaking the vial and storing it for only 24 hours at 30°C - 40°C.   Once the crystals are re-dissolved, the product may be used. 

Dispose of unused product or containers in accordance with guidance from your local waste regulation authority, e.g. the local regional office of the Environment Agency or SEPA.

Legal category

POM-V

Package quantities 

Dimazon 5% solution 10ml multi-dose bottle and 5×10ml.   Not all presentations may be marketed.

Further information 

Clinical experience with dogs indicates that improved results can frequently be achieved by supplementary administration of corticosteroids. 

Marketing authorisation number

Vm 01708/4406

Marketing Authorisation holder

Intervet UK Ltd.                

Walton

Milton Keynes

Buckinghamshire MK7 7AJ

Distributed in Northern Ireland by:

Intervet Ireland Ltd.

Magna Drive

Magna Business Park

Citywest Road

Dublin24

Date of text preparation: 

August 2005

Item code: 000533