Nobivac Forcat Data Sheet

Presentation

Freeze-dried live attenuated vaccine, containing per dose at least 4.6 log₁₀  pfu* of FCV strain F9; 5.2 log₁₀ pfu of FHV-1 strain G2620A; 4.3 log₁₀ CCID₅₀** of FPL virus strain MW-1 and 2.3 log₁₀ CCID₅₀  of Chlamydophila felis  strain Baker. 

Uses

Active immunisation of cats:

• to reduce the clinical signs caused by infection with feline calicivirus and feline herpes virus type 1 (feline rhinotracheitis virus).
  
• to reduce the severity of the clinical signs caused by infection with Chlamydophila felis (feline Chlamydia psittaci).
  
• to prevent the clinical signs, leucopenia and virus excretion caused by infection with feline panleucopenia virus. 

Onset of immunity: for FCV and FHV: 4 weeks; for FPLV and Chl. felis: 3 weeks.

Duration of immunity for FCV, FHV, Chl. felis: 1 year; for FPLV: 3 years.

Dosage and administration

Administer one dose per animal (1 vial of vaccine reconstituted with 1 vial of solvent).

Reconstitute the vaccine immediately before use with the accompanying solvent.

Inject 1 vial of solvent into a vaccine vial and shake gently until the vaccine pellet is completely dissolved.

Administer 1 ml reconstituted vaccine by subcutaneous injection.

Use sterile injection equipment, free from traces of disinfectants.

Vaccination schedule:

Basic vaccination:

Two single dose inoculations, 3-4 weeks apart.

The first inoculation can be given from the age of 8-9 weeks and the second inoculation from the age of 12 weeks.

Revaccination:

A single dose (1 ml) according to the following schedule:

Revaccination against feline calicivirus, feline herpesvirus type 1 and Chlamydophila felis must be given every year (with Nobivac Forcat or other vaccines containing the F9, G2620 or Baker strains, where available).

Revaccination against feline panleucopenia virus can be given every three years (with strain MW-1 as in Nobivac Forcat).

Contra-indications, warnings, etc.

Do not use during pregnancy or lactation, as the product has not been tested in pregnant or lactating queens. Live FPL virus can cause reproductive problems in pregnant queens and birth defects in the progeny.

A slight painful swelling may be observed at the injection site for 1-2 days. A slight transient rise in body temperature (up to 40°C) may occur for 1-2 days. In some cases sneezing, coughing, nasal discharge and a slight dullness or reduced appetite may be observed for up to 2 days post vaccination.

If you notice any serious effects not mentioned in the leaflet or data sheet, please inform your veterinary surgeon.

Vaccinate only healthy animals.

Maternal antibodies, which may persist up to the age of 9-12 weeks, can have a negative influence on the efficacy of vaccination. In the presence of maternal antibodies, vaccination may not completely prevent the clinical signs, leucopenia and virus excretion following an FPLV infection, and may reduce protection against Chl. felis infection. In such cases where a high level of maternally derived antibodies is expected, the vaccination schedule should be planned accordingly. 

No information is available on the safety and efficacy from the concurrent use of this vaccine with any other. It is therefore recommended that no other vaccines should be administered within 14 days before or after vaccination with this product.

Do not mix with any other veterinary medicinal product (except the diluent supplied for use with the product).

Because antimicrobials may inactivate the live Chl. felis vaccine strain, systemic antimicrobial therapy should be avoided during vaccination and for a two week period afterwards.

The Chl. felis vaccine strain may be excreted by vaccinated cats for more than 21 days and may be transmitted to non-vaccinated animals without inducing clinical signs.

Operator warnings:

It is advised that immunodeficient persons or persons taking immunosuppressive drugsdo not handle this vaccine. Owners should be made aware that some vaccinated cats may excrete the organism.

In case of accidental self injection, seek medical advice immediately and show the package leaflet or the label to the physician, referring to the live chlamydial component.

Withdrawal period:   Not applicable.

FOR ANIMAL TREATMENT ONLY.  KEEP OUT OF REACH AND SIGHT OF CHILDREN.

Pharmaceutical precautions

Freeze-dried vaccine: Store between +2°and +8°C. Protect from light.

Solvent: if stored separately, store below 25°C. Do not freeze.

Reconstituted product: use within 30 minutes.

Do not use after the expiry date which is stated on the label.

Disposal advice:

Dispose of waste material by boiling, incineration or immersion in an appropriate disinfectant in accordance with national requirements.

Package quantities

Carton with 5, 10, 25 or 50 single dose vials of vaccine and solvent.

Not all presentations may be marketed.

Legal category

POM-V                          To be supplied only on veterinary prescription.

Marketing Authorisation holder

Intervet International B.V. represented by:

Intervet UK Ltd.

Walton Manor

Walton

Milton Keynes

Bucks MK7 7AJ

Marketing Authorisation number

Vm 06376/4050            UKAuthorised veterinary medicinal product.

Manufacturer

Intervet International BV

Wim de Körverstraat 35

NL-5831 AN Boxmeer

Date of text preparation:

21 December 2005.

*pfu: plaque forming units **CCID₅₀:cell culture infective dose